How to choose a biochemical analyzer?
When most people want to introduce a biochemical analyzer, they may feel that it is difficult to choose. There are so many brands of biochemical analyzers, how should they choose?
This article has sorted out some knowledge about biochemical analyzers, and I hope to give you a reference when choosing a biochemical analyzer, I hope it will be helpful.
Classification of biochemical analyzers
According to the degree of automation, biochemical analyzers can be divided into two categories
1. Semi-automatic biochemical analyzer: Some operations in the analysis process (such as sample addition, heat preservation, inhalation colorimetry, result recording, etc.) need to be completed manually, while other operations can be completed automatically by the instrument.
2. Fully automatic biochemical analyzer: The entire process from sample addition to result output is completely automated by the instrument. The operator only needs to place the sample on the reagent placement position of the analyzer, and select the program to start the instrument to wait for the test report. The fully automatic biochemical analyzer has a high degree of automation and has the functions of calibration and automatic correction, so the errors are relatively small, the results are more accurate, and the use is more convenient.
According to the structure of the reaction device, automatic analyzers can be divided into the following categories:
1. Flow type: (pipeline type) The first-generation automatic biochemical analyzer mainly adopts the flow type. The flow type means that the chemical reaction of each sample to be tested and the reagent with the same measurement item is completed in the process of flowing in the same pipeline. .
2. Discrete: Refers to the chemical reaction after each sample to be tested and reagents are mixed in their respective reaction cups
Most of the automatic biochemical analyzers currently used in clinical laboratories are discrete and have the advantages of simple structure and fast detection speed.
3. Centrifugal: It means that each sample to be tested is mixed with reagents in its respective reaction tank under the action of centrifugal force to complete the chemical reaction and measure.
shortcoming:
The same centrifuge plate can only analyze one item at the same time; the reaction plate has no automatic cleaning function; the analysis speed is slow.
Solid-phase reagent self-determined biochemical analyzer (also known as dry chemical automatic analyzer) is to solid-phase reagents on a carrier such as film or filter paper, and drop each sample to be tested on the corresponding test strip for reaction and measurement. Dry chemical analyzer has the advantages of quick operation and easy portability
4.Bag type: refers to the use of reagent bags instead of reaction cups and cuvettes, and each sample to be tested is reacted and measured in its own reagent bag;
What factors need to be considered when choosing a biochemical analyzer?
Accuracy
The problem that everyone pays most attention to when choosing a biochemical analyzer is undoubtedly the problem of accuracy. The results are inaccurate, and the whole bunch of fancy things are useless.
The level of accuracy is closely related to the core technology behind the instrument. Biochemistry can be divided into "dry" and "wet". As we have mentioned before, the dry method uses the liquid in the sample to be tested as the reaction medium, and the test object directly A detection method that reacts with a dry powder reagent solidified on a carrier.
Wet biochemical means that all reactions are carried out in liquid, and "dry" is relative to "wet".
So, what is the difference between dry and wet?
- The sample size should be as small as possible
Whether it is medical diagnosis or pet diagnosis, there is a problem of difficulty in blood collection. In medical diagnosis, blood collection for infants and young children and blood collection for patients with anemia may be difficult.
In pet diagnosis, it is difficult for some exotic pets to collect blood, and owners will feel distressed when they see too much blood from their pets.
Therefore, it is undoubtedly an advantage that the sample size required by the biochemical analyzer is as small as possible.
- The operation should be as simple as possible:
The steps of the operation should be controlled within 3 steps as much as possible, and the operation can be started without professional training as much as possible, so as to reduce the cost of manual training.
- Less maintenance work
Generally, the quality control and maintenance of large-scale instruments will be more complicated. When the accuracy of instrument detection can be ensured, the maintenance cost should be minimized. Instruments with less maintenance work or maintenance-free are preferred.
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