What is the Development of microplate reader?
The microplate reader is also called enzyme-linked immunosorbent assay, which is a special instrument for enzyme-linked immunosorbent test and belongs to a category of life science instruments. The basic working principle of the microplate reader is similar to the main structure and photoelectric colorimeter. According to the degree of automation of the instrument, the microplate reader can be simply divided into two categories: semi-automatic and fully automatic; according to its working principle, microplate readers can be divided into grating type microplate reader and filter type microplate reader, among which, the grating type The microplate reader can intercept any wavelength within the range of the light source, while the filter-type microplate reader is limited to optional filters and can only intercept specific wavelengths for detection.
Microplate readers are widely used in medical testing, life sciences, agricultural sciences, food sciences, environmental sciences and other fields. The user groups include quality inspection institutions, blood stations, medical institutions, universities, scientific research institutes, etc., and the market prospects are broad. In recent years, China has issued a series of policies to encourage technological innovation. The fields of life and medical sciences have shown a good development trend. The industry of microplate readers and other related equipment has developed rapidly, and the market scale has continued to expand.
According to the "In-depth Evaluation of China's Microplate Reader Industry Market and Investment Feasibility Consultation Report for 2021-2025" issued by the Xinsijie Industry Research Center, the microplate reader is a necessary analysis for the characterization, functional research, mechanism exploration and application development of engineering antibodies. equipment. In recent years, with the development of medical testing, life sciences, agricultural sciences, food sciences, environmental sciences and other fields, the interaction and cooperation between disciplines have become closer, and users have continuously improved the performance requirements of microplate readers, prompting microplate reader manufacturers to continue to develop new products. , The product types and functions of microplate readers are becoming more and more diversified. New products such as multifunctional microplate readers (that is, a single desktop microplate reader with multiple detection modes) are continuously being introduced to the market, which can realize absorbance, fluorescence intensity, and time-resolved fluorescence. , Fluorescence polarization and chemiluminescence and other one-stop detection, improve scientific research and work efficiency in the application field.
The industry researcher of Xinsijie said that the current maturity of China's microplate reader industry is still relatively ordinary, and there is still a certain gap between the relevant core technology and product quality performance and the international advanced level. Taking the multifunctional microplate reader as an example, foreign brand products can realize multifunctional and highly sensitive microplate detection based on grating continuous spectroscopy, and the detection accuracy can reach the level of picogram to femtogram. Conventional detection items can include light absorption, chemiluminescence, Fluorescence intensity, fluorescence resonance energy transfer (FRET), and support for the expansion of multiple detection modes such as endpoint method, kinetic method, spectrum scanning, hole scanning, etc., which can meet biochemical analysis, immunoassay, cell research, drug screening and mechanism exploration at the same time Testing needs in many fields. In contrast, most domestic equipment can only detect single absorbance, the detection sensitivity is only nanogram level, the detection dynamic range is also narrow, usually no more than 3 orders of magnitude, and does not have the function of fluorescence resonance energy transfer (FRET) , It is difficult to meet the current experimental requirements for multi-mode, ultra-micro, and complex state of cells, and further development is needed in the future.
