Ethylene Oxide Sterilizer:
Ethylene oxide sterilizer is often used for fumigating food, textiles and other heat-unstable drugs and surgical equipment that cannot be disinfected by other methods, such as leather, cotton products, chemical fiber fabrics, precision instruments, biological products, paper, books, documents, some drugs, rubber products, etc.
Sterilization Principle of Ethylene Oxide Sterilizer:
Strong penetration of disinfection articles, can reach deep articles, can kill most pathogenic microorganisms, including bacterial propagules, spores, viruses and fungi. Both gas and liquid have strong microbicidal effect, and the effect of gas is stronger, so the gas is used. It is believed that ethylene oxide kills microorganisms due to its nonspecific alkylation with microbial proteins, DNA and RNA. Take protein as an example, the carboxyl, amino, thio-hydrogen and hydroxyl groups on the protein are alkylated, so that the normal biochemical reaction and metabolism of the protein are blocked, resulting in the death of microorganisms. Ethylene oxide is hydrolyzed into ethylene glycol, which also has a certain bactericidal effect.
Note:
Ethylene oxide is harmless to most disinfection items. Some components in food can be destroyed, such as vitamins B1, B2, B6 and folic acid, and the content of histidine, methionine, lysine and so on in food after disinfection is reduced. The efficacy of streptomycin was reduced by 35% after sterilization with ethylene oxide, but it had no inactivation effect on penicillin. This product cannot be used for sterilization of blood because it can cause erythrocyte lysis, complement inactivation and destruction of prothrombin.
